If you're wondering how to give puppy shots at home, or if you want to vaccinate your own pup (or dog), this page has all the information you need to get it done right.

Puppy shots are not optional, they're essential.....
They protect your new puppy from a host of serious, potentially deadly, dog illnesses, including Parvo, Distemper, Leptospirosis, Coronavirus, Hepatitis and more.
Most dog owners take their puppies and dogs to their veterinarian to get their puppy vaccinations, but if you are comfortable with the thought of vaccinating a puppy yourself it can save you time and money.
* If you're a breeder you can save even more by vaccinating your litters yourself.
Quick Links:
But, this isn't for everyone and you need to make sure that you are going to be okay about injecting a needle into your precious puppy.
Also, talk to your vet first, plus read ALL the instructions and follow them carefully... that way your puppy is kept safe at all times.You can find tons of information on the types of canine vaccinations your puppy needs, and the illnesses that they guard against on my main Puppy Shots page. Even if you are vaccinating a puppy yourself, the same vaccines are needed.
An important part of the 'how to give puppy shots at home' information is knowing which vaccines your pup needs (and when he needs them). Here is a quick recap of the recommended puppy vaccinations and the puppy vaccination timeline to follow...
Generally a pup will receive either a 5-way 'combo' vaccine or a 7-way combo. These vaccines protect against a number of different diseases.
5-Way Canine Vaccine (aka DHLPP) usually includes:
7-way Canine Vaccine normally include all of the above, plus protection against additional strains of adenovirus, leptospirosis, and coronavirus.
You will need to check the product information on the particular combo vaccine you buy to be sure you know what it contains.
There are also additional vaccinations that your dog may need to have, depending on the area you live in and more.
These may include Lyme Disease and Giardia.
If your pup is going to be kenneled, attend training classes or doggie-daycare, visit the dog park or other public places often and generally be a 'social butterfly' (which is good!) you will need to protect him against Kennel Cough (with the Bordetella vaccine)
There are two options for this, either give him a 'shot' or use nasal drops. The intra-nasal method gives faster protection and doesn't need to be repeated 3 or 4 weeks later the way the shot does.
Whichever option you choose, if your pup is regularly in contact with many other dogs you should dose him twice a year (every six months) rather than waiting for a yearly booster.
Rabies is a vaccination all dogs must have by law, but it needs to be given by a licensed veterinarian.
You can purchase the vaccines from feed stores or online. Here are some of the most popular ones...
For large/giant breed puppies and dogs, the recommended size of syringe would be 3/4" X 22 ga for subcutaneous shots and 1" X 22 ga for intramuscular ones.
For small/young puppies and kittens, the 5/8" X 22 ga is usually better.
You can also buy vaccines for cats and kittens, horses and livestock. To see more options check out this page...... Vaccines.
Vaccines need to be kept refrigerated or they can become ineffective.
When you order online, vaccines will come in a cooler of some sort with a gel ice-pack (buy extra ice-packs in hot weather) but I'd still recommend choosing speedy shipping options.
Put them directly into your refrigerator as soon as you receive them.
Usually you want to begin your puppy's vaccinations when he's between 6 and 8 weeks old.
Some high-risk breeds, or puppies in large kennels, may need to be vaccinated earlier (at around 5 weeks old) to protect against Parvovirus.
Here is a 'puppy shots timeline' to use as a guideline:
Puppy's Age |
Vaccination/s |
| 6 - 8 weeks | Combination vaccine - it's often recommended NOT to use one with Leptospirosis for puppies under 12 weeks old.. |
| 9 - 12 weeks | Combination vaccine plus Coronavirus and Lyme Disease if necessary |
| 12 - 15 weeks | Combination Vaccine plus Coronavirus and Lyme Disease if necessary |
| After 16 weeks | Rabies vaccine. Additional Parvo shot should be given for high-risk breeds (such as Rottweilers, Doberman Pinschers and Pitbulls) 3 weeks after the third one was administered. |
| Annually (or every 3 years) | 'Booster' shots (the combo and Rabies) should be given either annually or every 3 years depending on the local law and exact vaccine chosen. |
But please remember, this puppy vaccination schedule is a guideline only. It's always a good idea to check with your veterinarian before deciding on the type of vaccinations and the timeline you plan to use.
There can be variations depending on the breed and age of the puppy (and any health concerns) and the area that you live in.
Also, bear in mind that just because your puppy has had one set of vaccinations (or even two or more), immunity isn't 'instant' neither is it guaranteed!
In general it takes somewhere between one and two weeks for the vaccine to take effect, or depending on the age of the puppy the antibodies still circulating in his blood from his momma may interfere with their effectiveness.
This is why three sets of shots, at three week intervals is recommended.
If you've decided that you're ready to learn more about how to give puppy shots at home and want to get started, it's important to make sure that you understand how to do it correctly, and what safety precautions to follow.
It's a good idea to have two people involved if possible as you will need someone to hold your pup still while you do the injection (or vice versa).
Although it may be a bit stressful for you to put that needle into your puppy's skin, it will actually be LESS stressful for him as he won't have the added anxiety of being in the veterinarian's office surrounded by strange people, smells and sounds.
Before we go into the details of how to give puppy shots at home properly, here's a quick overview of how to get prepared...
Some vaccines come in two vials, one of liquid and one of powder. Before you can give the shot you need to mix both components.
Step 1
To
do this simply insert the needle into the vial of liquid and slowly and
gently pull up the plunger. The body of the syringe should fill with
liquid. Once you've got all the liquid into the syringe, remove it from
the empty vial.
Step 2
Push the syringe into the second
vial which contains the powder. Push down on the plunger so that the
liquid empties into this second vial completely, then pull out the
syringe.
Step 3
Shake the vial well so that the powder
until the powder and liquid are thoroughly mixed together (make sure all
the powder has completely dissolved and that there are no lumps).
Step 4
Re-insert
the syringe into the vial and draw the mixture up by pulling back on
the syringe (as you did with the liquid the first time). If you draw up
any air after the liquid, gently push down on the plunger until you push
it back out. Now remove the syringe from the vial completely and you're
all set.
If the vaccine you are using came premixed, or as single vial of liquid, then you don't have to worry about all the mixing! Either way, at this point you are ready to really learn how to give puppy shots at home!
NOTE: You need to use all the liquid/powder that is supplied. Don't think because you have a tiny/toy breed that you will need to use less than a complete dose. All dogs need the full amount of vaccine, regardless of their size, age or breed.
There are 4 methods of how to give puppy shots, at home or when done by a veterinarian or vet tech, vaccines, they are.... intramuscular (directly into a muscle), intravenous (directly into a vein) and intra-nasal (drops into the nose).
Most routine puppy shots are given subcutaneously (the easiest method), but the Rabies vaccine is an intramuscular one. Never try to give an intramuscular or intravenous vaccination yourself, those MUST to be left to a professional!
The Bordetella is given intranasally, or as a subcutaneous injection, and sometimes is combined with other vaccines such as parainfluenza or leptospirosis.
The normal puppy shots that we're talking about here can be given subcutaneously and here is a quick run-down of how to do it (please read through at least once, then watch the 'how to give puppy shots at home' video, before you start):
When you're all finished don't forget to dispose of the vaccine vials and the needles safely.
Also, always use a fresh syringe/needle for each pup or each vaccination.
Although it may seem a bit scary at first, learning how to give puppy shots at home is pretty straightforward... and it does get easier with practice. If you have a whole litter to do, you'll be feeling like a pro by the time you're done!
However something that you need to be aware of when vaccinating a pup yourself is that there is a possibility of the pup having an adverse reaction of some sort.
Many puppies have a mild reaction to their puppy shots, and a lump or swelling at the site of the injection itself is very common. This may only last a few hours or days, or it can stick around for weeks. As long as it's not red, inflamed or showing signs of infection this isn't anything to worry about.
Other very common side effects of puppy vaccines include a day or two of drowsiness, loss of appetite, maybe loose stools and sometimes some localized pain.
More severe reactions can include hives, or localized or generalized swelling of the head, body even occasionally disorientation or seizures.
If you see any swelling start after you've given your pup his shots, you need to have a vet take a look at him immediately as he may need corticosteroids or antihistamines to deal with it.
A really severe allergic reaction can cause difficulty breathing, seizures and even, in rare cases, death. So never take any chances!
If this does happen, future vaccinations should be given at the veterinarian's office so that he can be monitored.
Also, some breeds are more prone to allergic reactions than others, and may be hyper-sensitive to the components in some vaccines. These breeds include
Akita
American Cocker Spaniel
Australian Shepherd
Dachshund
German Shepherd
Golden Retriever
Great Dane
Irish Setter
Kerry Blue Terrier
Old English Sheepdog
Poodle
Portuguese Water Dog
Scottish Terrier
Shetland Sheepdog
Shit Tzu
Vizla
Weimeraner
West Highland White Terrier
The vaccines for Rabies, Parvovirus and Leptosirosis seem to be more likely to cause problems, but it's possible for a reaction to occur to any vaccine.
If you have one of these more susceptible breeds I would strongly recommend discussing your desire to learn more about how to give puppy shots at home with your vet before going ahead.
If you are committed to vaccinating a puppy yourself who is of a susceptible breed, you should have some epinephrine handy (and know how to use it), just to be safe. Discuss this with your vet also.
If you have any questions about how to give puppy shots at home, or about puppy vaccinations in general (or any other pet related veterinary question for that matter!), you can get a quick, professional answer by using the question box below...